SCHEMBL30455325

SCHEMBL30455325

CSCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)O)C(C)C)C(C)C

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ EPHA2 P29317 2/20 0.57
▸ CALCR P30988 5/20 0.54
▸ RAMP3 O60896 3/20 0.54
▸ OPRM1 P35372 2/20 0.53
▸ OPRD1 P41143 2/20 0.53
▸ C5AR1 P21730 1/20 0.53
▸ NMUR2 Q9GZQ4 3/20 0.52
▸ NMUR1 Q9HB89 3/20 0.52
▸ APLNR P35414 1/20 0.51
▸ MC4R P32245 1/20 0.51
▸ MC5R P33032 1/20 0.51
▸ MC3R P41968 1/20 0.51
▸ MC1R Q01726 1/20 0.51
▸ NPY1R P25929 1/20 0.51
▸ NPY2R P49146 1/20 0.51
▸ NPY4R P50391 1/20 0.51
▸ NPY5R Q15761 1/20 0.51
▸ IL23R Q5VWK5 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32679453 0.90 C5AR1 (0.56) EPHA2CALCRRAMP3OPRM1OPRD1
SCHEMBL30454832 0.89 EPHA2 (0.57) EPHA2
SCHEMBL30584470 0.88 EPHA2 (0.56) EPHA2CALCRRAMP3OPRM1OPRD1
SCHEMBL30883247 0.85 RAMP3 (0.57) EPHA2CALCRRAMP3C5AR1NMUR2
SCHEMBL29561936 0.85 NMUR2 (0.64) EPHA2CALCRRAMP3NMUR2NMUR1
SCHEMBL30906437 0.85 EPHA2 (0.61) EPHA2CALCRRAMP3NMUR2NMUR1
SCHEMBL31307232 0.84 EPHA2 (0.56) EPHA2CALCRRAMP3OPRM1OPRD1
SCHEMBL30906381 0.84 NPY2R (0.63) EPHA2CALCRRAMP3NPY1RNPY2R
SCHEMBL32670411 0.84 EPHA2 (0.68) EPHA2CALCRRAMP3OPRM1OPRD1
SCHEMBL30335928 0.84 EPHA2 (0.68) EPHA2CALCRRAMP3OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023122721-A2 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (US) 2023-06-29 — — WO claimed
US-20240343760-A1 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (OR) 2024-10-17 — — US disclosed
WO-2023122721-A2 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA OREGON STATE UNIVERSITY (US) 2023-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343760-A1 PEPTIDES FOR CELL-TYPE SPECIFIC TARGETING OF THE RETINA ARGLU1, TPX2, RXFP1 EPHA2 1164/4885CALCR 706/4885RAMP3 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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