Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27388251 | 1.00 | POLB (0.35) | POLBGAACHRM2CHRM1MEN1 | |
| SCHEMBL24145355 | 0.88 | POLB (0.38) | POLBGAACHRM2CHRM1MEN1 | |
| SCHEMBL17928956 | 0.88 | POLB (0.38) | POLBGAACHRM2CHRM1MEN1 | |
| SCHEMBL220405 | 0.88 | POLB (0.38) | POLBGAACHRM2CHRM1MEN1 | |
| SCHEMBL6475002 | 0.88 | POLB (0.38) | POLBGAACHRM2CHRM1MEN1 | |
| SCHEMBL20329541 | 0.88 | POLB (0.38) | POLBGAACHRM2CHRM1MEN1 | |
| SCHEMBL8544746 | 0.86 | CHRM2 (0.37) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL8567305 | 0.86 | CHRM2 (0.37) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL10440862 | 0.81 | CHRM2 (0.42) | POLBGAACHRM2CHRM1MEN1 | |
| SCHEMBL14627937 | 0.75 | CHRM2 (0.38) | CHRM2CHRM1MEN1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157853-A1 | GUT MICROBIOTA BIOACTIVATED PDE4 INHIBITOR PRECURSORS | Giiant Pharma Inc. (CA) | 2023-04-05 | — | — | EP | disclosed |