SCHEMBL220405

SCHEMBL220405

CC(=O)OC1COCC(OC(C)=O)C1OC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
CHRM2 P08172 5/20 0.38
CHRM1 P11229 3/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
CYP2D6 P10635 1/20 0.38
CHRM4 P08173 2/20 0.35
CHRM3 P20309 2/20 0.35
TSHR P16473 1/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
BCHE P06276 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24145355 1.00 POLB (0.38) POLBGAACHRM2CHRM1KMT2A
SCHEMBL6475002 1.00 POLB (0.38) POLBGAACHRM2CHRM1KMT2A
SCHEMBL17928956 1.00 POLB (0.38) POLBGAACHRM2CHRM1KMT2A
SCHEMBL20329541 1.00 POLB (0.38) POLBGAACHRM2CHRM1KMT2A
SCHEMBL10440862 0.88 CHRM2 (0.42) POLBGAACHRM2CHRM1KMT2A
SCHEMBL30454878 0.88 POLB (0.35) POLBGAACHRM2CHRM1KMT2A
SCHEMBL29189673 0.82 CHRM2 (0.38) CHRM2CHRM1KMT2AMEN1CYP2D6
SCHEMBL14627937 0.82 CHRM2 (0.38) CHRM2CHRM1KMT2AMEN1CYP2D6
SCHEMBL24752585 0.82 CHRM2 (0.38) CHRM2CHRM1KMT2AMEN1CYP2D6
SCHEMBL29189672 0.82 CHRM2 (0.38) CHRM2CHRM1KMT2AMEN1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118894896-A Method for preparing nematodoside and xyloside dimeric pheromone 云南大学 2024-11-05 CN claimed
WO-2023278827-A1 3-IODOPROPYL-1,2,3-TRIAZOL-1-YL, 3-BROMOPROPYL-1,2,3-TRIAZOL-1-YL, AND DERIVATIVES FOR USES IN LABELING EMORY UNIVERSITY (US) 2023-01-05 WO claimed
EP-2091941-A2 MAPK/ERK KINASE INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2009-08-26 EP claimed
WO-2008140553-A2 MAPK/ERK KINASE INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-11-20 WO claimed
US-20080125437-A1 MAPK/ERK KINASE INHIBITORS TAKEDA SAN DIEGO, INC. 2008-05-29 US claimed
EP-4701666-A1 ANTIBODY-DRUG CONJUGATE COMPOUNDS, AND METHODS OF USE AND TREATMENT Iksuda Therapeutics Limited (GB) 2026-03-04 EP disclosed
EP-4694936-A1 STEAP2 ANTIBODY DRUG CONJUGATES AND USES THEREOF MedImmune, LLC (US) 2026-02-18 EP disclosed
EP-4661912-A1 LINKER FOR ANTIBODY-DRUG CONJUGATE Pinotbio, Inc. (KR) 2025-12-17 EP disclosed
EP-4651911-A1 NEW SENESCENCE TRACER GENERATION Eberhard Karls Universität Tübingen, Medizinische Fakultät (DE) 2025-11-26 EP disclosed
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES Illudent, Inc. (US) 2025-09-25 US disclosed
EP-4583870-A2 MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER Mito Biopharma, LLC (US) 2025-07-16 EP disclosed
WO-2025124456-A1 ANTIBODY DRUG CONJUGATE PLATFORMS BEIGENE, LTD. (KY) 2025-06-19 WO disclosed
US-20100204471-A1 MAPK/ERK KINASE INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-08-12 US disclosed
US-20100113413-A1 MAPK/ERK Kinase Inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-05-06 US disclosed
US-7696218-B2 Substituted 1,3-dialkyl-2,4-dioxo-6-(arylamino)-1,2,3,4-tetrahydropyrimidine-5-hydroxamic acid inhibitors of MAPK/ERK kinase TAKEDA SAN DIEGO, INC. (US) 2010-04-13 US disclosed
EP-2091941-A2 MAPK/ERK KINASE INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2009-08-26 EP disclosed
US-20090176859-A1 Cathepsin cysteine protease inhibitors MERCK FROSST CANADA, LTD. (CA) 2009-07-09 US disclosed
US-20090176859-A1 Cathepsin cysteine protease inhibitors MERCK FROSST CANADA, LTD. (CA) 2009-07-09 US disclosed
WO-2008140553-A2 MAPK/ERK KINASE INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-11-20 WO disclosed
US-20080125437-A1 MAPK/ERK KINASE INHIBITORS TAKEDA SAN DIEGO, INC. 2008-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES OGFR, TNFSF11, FCER2 POLB 1348/4885GAA 308/4885CHRM2 2352/4885
US-20100204471-A1 MAPK/ERK KINASE INHIBITORS MAPK1, MAP3K1, MAP3K7 POLB 1774/4885GAA 2792/4885CHRM2 4693/4885
US-20080125437-A1 MAPK/ERK KINASE INHIBITORS MAPK1, MAP3K1, MAP3K7 POLB 1774/4885GAA 2792/4885CHRM2 4693/4885
US-20090176859-A1 Cathepsin cysteine protease inhibitors CTSE, CTSB, CTSS POLB 3690/4885GAA 549/4885CHRM2 941/4885
US-20100113413-A1 MAPK/ERK Kinase Inhibitors MAPK1, MAPK6, MAPK4 POLB 2121/4885GAA 2772/4885CHRM2 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.