SCHEMBL8567305

SCHEMBL8567305

CC(=O)OC1COCC1O

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 5/20 0.37
CHRM1 P11229 3/20 0.37
KMT2A Q03164 2/20 0.37
CYP2D6 P10635 2/20 0.37
MEN1 O00255 1/20 0.37
CHRM4 P08173 2/20 0.34
CHRM3 P20309 2/20 0.34
TSHR P16473 1/20 0.33
BCHE P06276 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
METAP2 P50579 1/20 0.31
CYP2C19 P33261 1/20 0.30
ABL1 P00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8544746 1.00 CHRM2 (0.37) CHRM2CHRM1KMT2ACYP2D6MEN1
SCHEMBL10440862 0.86 CHRM2 (0.42) CHRM2CHRM1KMT2ACYP2D6MEN1
SCHEMBL27388251 0.86 POLB (0.35) CHRM2CHRM1KMT2ACYP2D6MEN1
SCHEMBL30454878 0.86 POLB (0.35) CHRM2CHRM1KMT2ACYP2D6MEN1
SCHEMBL10392136 0.82 ABL1 (0.34) BCHEABL1
SCHEMBL10392135 0.82 ABL1 (0.31) ABL1
SCHEMBL1866864 0.80 ALDH1A1 (0.41) TSHR
SCHEMBL24752585 0.80 CHRM2 (0.38) CHRM2CHRM1KMT2ACYP2D6MEN1
SCHEMBL220405 0.80 POLB (0.38) CHRM2CHRM1KMT2ACYP2D6MEN1
SCHEMBL17928956 0.80 POLB (0.38) CHRM2CHRM1KMT2ACYP2D6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744426-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-04-28 US disclosed
EP-0548593-B1 Tetrahydrofuran derivative and herbicide containing the same as effective ingredient MITSUBISHI CHEM CORP (JP) 1998-04-22 EP disclosed
CN-1152305-A Substituted 3-phenylpyrazoles as herbicides BASF AG (DE) 1997-06-18 CN disclosed
EP-0763025-A1 SUBSTITUTED 3-PHENYLPYRAZOLES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-03-19 EP disclosed
WO-1995033728-A1 SUBSTITUTED 3-PHENYLPYRAZOLES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1995-12-14 WO disclosed
US-5405828-A Selective pre- and postemergence herbicides MITSUBISHI KASEI CORPORATION (JP) 1995-04-11 US disclosed
US-5324709-A Safety on crops MITSUBISHI KASEI CORPORATION (JP) 1994-06-28 US disclosed
EP-0548593-A1 Tetrahydrofuran derivative and herbicide containing the same as effective ingredient Mitsubishi Chemical Corporation (JP) 1993-06-30 EP disclosed