Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30454911

Nc1ccnnc1.O=C(O)C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.44
HSD17B10 Q99714 2/20 0.39
L3MBTL1 Q9Y468 3/20 0.35
C1S P09871 2/20 0.35
HRH4 Q9H3N8 2/20 0.34
HRH3 Q9Y5N1 2/20 0.34
HDAC4 P56524 2/20 0.34
PTGS1 P23219 1/20 0.33
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33
ITGB1 P05556 2/20 0.33
ITGA5 P08648 2/20 0.33
ITGA4 P13612 2/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KDM6B O15054 1/20 0.32
KDM4A O75164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29607630 0.78
SCHEMBL164220 0.78
Trifluoroacetic Acid SCHEMBL6386625 0.78 HCAR2 (0.55) HCAR2HSD17B10L3MBTL1MAPTKMT2A
Dalfampridine SCHEMBL21084451 0.78 MEN1 (0.56) L3MBTL1PTGS1KDM4EMEN1KDM6B
Trifluoroacetic Acid SCHEMBL27863366 0.78 HRH4 (0.37) L3MBTL1C1SHRH4HRH3CDK5
Trifluoroacetic Acid SCHEMBL30226472 0.77 HCAR2 (0.77) HCAR2L3MBTL1KDM4EKDM6BKDM4A
Hydrochloric Acid SCHEMBL15880559 0.76
Trifluoroacetic Acid SCHEMBL2481360 0.76 PLOD2 (0.46) HCAR2L3MBTL1CDK5CDK5R1MEN1
Trifluoroacetic Acid SCHEMBL30444900 0.76 PLOD2 (0.46) HCAR2L3MBTL1CDK5CDK5R1MEN1
Trifluoroacetic Acid SCHEMBL27673223 0.74 HCAR2 (0.41) HCAR2HSD17B10L3MBTL1ALDH1A1CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023121413-A1 NOVEL BICYCLIC HETEROCYCLYL COMPOUND AND USE THEREOF 제일약품주식회사 2023-06-29 WO disclosed