Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.67 |
| ▸ | FYN | P06241 | 7/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488061 | 1.00 | MET (0.67) | METFYNCHEK2PIK3CDPIK3CA | |
| SCHEMBL487956 | 0.89 | MET (0.76) | METFYNCHEK2MAP4K3MAP4K4 | |
| SCHEMBL30452741 | 0.85 | MET (0.63) | METFYNPIK3CDPIK3CAPIK3CB | |
| SCHEMBL488173 | 0.85 | MET (0.63) | METFYNPIK3CDPIK3CAPIK3CB | |
| SCHEMBL487572 | 0.85 | MET (0.73) | METFYNPIK3CDPIK3CAPIK3CB | |
| SCHEMBL487907 | 0.85 | MET (0.81) | METFYNPIK3CDPIK3CAPIK3CB | |
| SCHEMBL487619 | 0.84 | MET (0.71) | METFYNCHEK2MAP4K3MAP4K4 | |
| SCHEMBL30452558 | 0.84 | MET (0.71) | METFYNCHEK2MAP4K3MAP4K4 | |
| SCHEMBL487730 | 0.84 | MET (0.79) | METFYNPIK3CDPIK3CAPIK3CB | |
| SCHEMBL30454723 | 0.84 | MET (0.79) | METFYNPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |