Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488173 | 1.00 | MET (0.63) | METPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30454973 | 0.85 | MET (0.67) | METPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL488061 | 0.85 | MET (0.67) | METPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL487619 | 0.83 | MET (0.71) | METMEN1KMT2AMAP4K4FYN | |
| SCHEMBL30452558 | 0.83 | MET (0.71) | METMEN1KMT2AMAP4K4FYN | |
| SCHEMBL487806 | 0.82 | MET (0.60) | METJAK2MAP4K3 | |
| SCHEMBL30454267 | 0.82 | MET (0.60) | METJAK2MAP4K3 | |
| SCHEMBL487572 | 0.82 | MET (0.73) | METPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL487907 | 0.82 | MET (0.81) | METPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30454723 | 0.81 | MET (0.79) | METPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |