SCHEMBL30455046

SCHEMBL30455046

Fc1cc(Cl)ccc1COc1cc(N2CC=CCC2)c(F)cc1F

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 6/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 2/20 0.42
TBXA2R P21731 2/20 0.42
PTGS1 P23219 2/20 0.42
CYP2C19 P33261 2/20 0.42
PTGER3 P43115 2/20 0.42
PTGER2 P43116 2/20 0.42
MAPK14 Q16539 1/20 0.40
HPD P32754 3/20 0.39
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
MRGPRX4 Q96LA9 1/20 0.37
HTR1A P08908 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30209255 0.83 KDM4E (0.42) PTGER1CYP1A2CYP2C9TBXA2RPTGS1
Hydrochloric Acid SCHEMBL30209286 0.77 HPD (0.47) PTGER1CYP1A2CYP2C9TBXA2RPTGS1
Hydrochloric Acid SCHEMBL31306902 0.75 HPGD (0.36) PTGER1CYP1A2CYP2C9TBXA2RPTGS1
SCHEMBL28786604 0.74 MAPK14 (0.45) PTGER1CYP1A2CYP2C9TBXA2RPTGS1
SCHEMBL24320512 0.69 MAPK14 (0.52) MAPK14HPDHTR1A
SCHEMBL26914325 0.69 HTR1A (0.48) CYP1A2CYP2C9CYP2C19HTR1ASLC6A2
SCHEMBL31326162 0.69 HTR1A (0.48) CYP1A2CYP2C9CYP2C19HTR1ASLC6A2
SCHEMBL26908042 0.69 PTGER1 (0.48) PTGER1CYP1A2CYP2C9TBXA2RPTGS1
SCHEMBL2958672 0.69 PTGER1 (0.49) PTGER1CYP1A2CYP2C9TBXA2RPTGS1
Hydrochloric Acid SCHEMBL26914254 0.68 HTR1A (0.47) CYP1A2CYP2C9CYP2C19HTR1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113227068-B GLP-1R agonists and uses thereof 上海齐鲁锐格医药研发有限公司 2023-06-13 CN disclosed