Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.39 |
| ▸ | JAK3 | P52333 | 3/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15459491 | 0.75 | DHODH (0.56) | JAK2LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL15459494 | 0.74 | JAK2 (0.43) | JAK2JAK3PTK2KDM4EALDH1A1 | |
| SCHEMBL23029959 | 0.74 | AHR (0.50) | JAK2JAK3PTK2LMNAKMT2A | |
| SCHEMBL15459490 | 0.73 | SMPD3 (0.41) | JAK2PARP1TSHR | |
| SCHEMBL24857430 | 0.71 | LMNA (0.34) | JAK2JAK3PTK2LMNAKMT2A | |
| SCHEMBL24858405 | 0.71 | DYRK1A (0.34) | JAK2 | |
| Formic Acid SCHEMBL30454470 | 0.71 | HDAC6 (0.31) | LMNAKDM4EALDH1A1GLAGAA | |
| Formic Acid SCHEMBL30455255 | 0.71 | HRH3 (0.37) | LMNAKDM4EALDH1A1GLAGAA | |
| SCHEMBL21078299 | 0.70 | JAK2 (0.53) | JAK2JAK3PTK2LMNAKDM4E | |
| SCHEMBL2634589 | 0.68 | JAK2 (0.45) | JAK2JAK3PTK2LMNADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |