Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PCNA | P12004 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30772157 | 0.86 | POLB (0.46) | POLBALDH1A1ALOX15CES2GALR3 | |
| SCHEMBL6583906 | 0.81 | SRC (0.44) | POLBALDH1A1ALOX15HPGDKDM4E | |
| SCHEMBL15658116 | 0.80 | MAPT (0.46) | POLBALOX15CES2GALR3CYP1A2 | |
| SCHEMBL6456130 | 0.80 | AKR1B1 (0.52) | POLBALOX15CES2GALR3CYP1A2 | |
| SCHEMBL21582058 | 0.80 | ALOX15 (0.45) | ALDH1A1ALOX15CES2GALR3CYP1A2 | |
| SCHEMBL29738013 | 0.80 | AKR1B1 (0.52) | POLBALOX15CES2GALR3CYP1A2 | |
| SCHEMBL24802541 | 0.79 | POLB (0.59) | POLBALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL3822381 | 0.78 | POLB (0.45) | POLBALDH1A1NCEH1PCNALMNA | |
| SCHEMBL21437928 | 0.77 | EGFR (0.46) | ALDH1A1HPGDNPSR1LMNA | |
| SCHEMBL24803642 | 0.77 | TRPA1 (0.44) | ALDH1A1ALOX15HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |