SCHEMBL30455536

SCHEMBL30455536

NCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.58
EPHX2 P34913 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
TLR2 O60603 2/20 0.43
FABP7 O15540 1/20 0.41
FABP5 Q01469 1/20 0.41
CASP3 P42574 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31010250 1.00 KMT2A (0.58) KMT2AEPHX2SMN1; SMN2LMNATLR2
SCHEMBL20209153 1.00 KMT2A (0.58) KMT2AEPHX2SMN1; SMN2LMNATLR2
SCHEMBL19960742 1.00 KMT2A (0.58) KMT2AEPHX2SMN1; SMN2LMNATLR2
SCHEMBL15160679 1.00 KMT2A (0.58) KMT2AEPHX2SMN1; SMN2LMNATLR2
Hydrochloric Acid SCHEMBL21460614 0.99 KMT2A (0.57) KMT2AEPHX2SMN1; SMN2LMNATLR2
Hydrochloric Acid SCHEMBL16742394 0.99 KMT2A (0.57) KMT2AEPHX2SMN1; SMN2LMNATLR2
Hydrochloric Acid SCHEMBL30387296 0.99 KMT2A (0.57) KMT2AEPHX2SMN1; SMN2LMNATLR2
SCHEMBL30341663 0.99 KMT2A (0.59) KMT2AEPHX2SMN1; SMN2LMNATLR2
SCHEMBL2254751 0.99 KMT2A (0.59) KMT2AEPHX2SMN1; SMN2LMNATLR2
Hydrochloric Acid SCHEMBL5579268 0.97 KMT2A (0.58) KMT2AEPHX2SMN1; SMN2LMNATLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705299-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF Rayzebio, Inc. (US) 2026-03-11 EP disclosed
US-20240409573-A1 CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF PFIZER INC. (US) 2024-12-12 US disclosed
WO-2024229154-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF RAYZEBIO, INC. (US) 2024-11-07 WO disclosed
US-11993625-B2 Calicheamicin derivatives and antibody drug conjugates thereof PFIZER, INC. (US) 2024-05-28 US disclosed
US-20230173082-A1 ANTIBACTERIAL PRODUCTS UNIVERSITY OF LINCOLN (GB) 2023-06-08 US disclosed
US-11660350-B2 Antibacterial products UNIVERSITY OF LINCOLN (GB) 2023-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409573-A1 CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF STT3A, CLSPN, STT3B KMT2A 3063/4885EPHX2 3031/4885SMN1; SMN2 4268/4885
US-11660350-B2 Antibacterial products MSN, VAPA, SLC47A2 KMT2A 3289/4885EPHX2 3477/4885SMN1; SMN2 2804/4885
US-11993625-B2 Calicheamicin derivatives and antibody drug conjugates thereof STT3A, CLSPN, STT3B KMT2A 3063/4885EPHX2 3031/4885SMN1; SMN2 4268/4885
US-20230173082-A1 ANTIBACTERIAL PRODUCTS XIAP, CLSPN, SLC47A2 KMT2A 4141/4885EPHX2 2807/4885SMN1; SMN2 2914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.