Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CCR4 | P51679 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002509 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL15353101 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTCCR4 | |
| SCHEMBL16235832 | 0.88 | CCR4 (0.61) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16235449 | 0.83 | CCR4 (0.42) | MEN1KMT2AMAPTCCR4TDP1 | |
| SCHEMBL3294648 | 0.82 | AR (0.55) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL26210667 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL30482244 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL3300238 | 0.81 | S100A9 (0.54) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL3293668 | 0.79 | CCR4 (0.76) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL3293352 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |