SCHEMBL3294648

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3293352	0.89	ALDH1A1 (0.48)	CYP19A1MAPTALDH1A1SMN1; SMN2MEN1
	SCHEMBL29002509	0.82	ALDH1A1 (0.52)	MAPTALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL30455631	0.82	ALDH1A1 (0.52)	MAPTALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL20628168	0.81	AR (0.59)	ARCYP19A1MAPTALDH1A1MEN1
	SCHEMBL6039073	0.80	CCR4 (0.64)	ARCYP19A1LMNACCR4KDM4E
	SCHEMBL16235832	0.78	CCR4 (0.61)	MAPTALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL3293668	0.78	CCR4 (0.76)	MAPTALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL3294696	0.78	CCR4 (0.62)	MAPTALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL3299669	0.77	KMT2A (0.45)	MAPTALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL8752447	0.76	CYP19A1 (0.69)	ARCYP19A1MAPTALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.