Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17147113 | 0.83 | MMP1 (0.34) | MMP1MMP9MMP14CNR2 | |
| SCHEMBL17752523 | 0.81 | — | — | |
| SCHEMBL21348163 | 0.81 | — | — | |
| SCHEMBL5397200 | 0.81 | NPSR1 (0.46) | — | |
| SCHEMBL2490744 | 0.81 | NPSR1 (0.46) | — | |
| SCHEMBL25663370 | 0.79 | CNR2 (0.36) | MMP9CNR2ACACBCAPN1 | |
| SCHEMBL16360269 | 0.79 | CYP2C9 (0.42) | MMP1MMP9MMP14 | |
| SCHEMBL17919955 | 0.74 | MMP1 (0.39) | MMP1MMP9MMP14 | |
| SCHEMBL20730738 | 0.74 | SMN1; SMN2 (0.38) | ACACB | |
| SCHEMBL7725268 | 0.73 | MEN1 (0.43) | MMP1MMP9ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4453000-A1 | NOVEL AURISTATIN ANALOGS AND IMMUNOCONJUGATES THEREOF | Adcentrx Therapeutics Inc. (US) | 2024-10-30 | — | — | EP | disclosed |
| CN-118829645-A | Novel auristatin analogues and immunoconjugates thereof | 艾德森特克斯治疗股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118541378-A | Novel auristatin analogues and immunoconjugates thereof | 艾德森特克斯治疗股份有限公司 | 2024-08-23 | — | — | CN | disclosed |
| WO-2023122228-A1 | NOVEL AURISTATIN ANALOGS AND IMMUNOCONJUGATES THEREOF | ADCENTRX THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | disclosed |