SCHEMBL16360269

SCHEMBL16360269

CCC(=O)N[C@H](C(=O)NC)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.42
MMP1 P03956 5/20 0.39
MMP9 P14780 4/20 0.39
MMP14 P50281 2/20 0.39
MMP2 P08253 7/20 0.34
MMP3 P08254 6/20 0.34
MMP8 P22894 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MMP13 P45452 1/20 0.34
ADAM17 P78536 1/20 0.34
HTT P42858 1/20 0.34
MMP7 P09237 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13888704 0.84 ALDH1A1 (0.42) CYP2C9ALDH1A1
SCHEMBL13758669 0.82 CYP2C9 (0.41) CYP2C9ALDH1A1HTTNPSR1
SCHEMBL21348163 0.82
SCHEMBL17752523 0.82
SCHEMBL19776873 0.79 CYP2C9 (0.38) CYP2C9
SCHEMBL13626169 0.79 CYP2C9 (0.38) CYP2C9MMP2MMP3ALDH1A1
SCHEMBL8628508 0.79 CYP2C9 (0.38) CYP2C9MMP2MMP3ALDH1A1
SCHEMBL17919955 0.79 MMP1 (0.39) MMP1MMP9MMP14
SCHEMBL30455965 0.79 MMP1 (0.39) MMP1MMP9MMP14
SCHEMBL17860258 0.79 CYP2C9 (0.38) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2813512-B1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI PHARMACEUTICAL CO LTD (JP) 2021-03-31 EP disclosed
US-20190330444-A1 SILICON-CONTAINING HALOGENATED ELASTOMERS 3M INNOVATIVE PROPERTIES COMPANY 2019-10-31 US disclosed
WO-2013100132-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD 中外製薬株式会社 (JP) 2013-07-04 WO disclosed