Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 17/20 | 0.60 |
| ▸ | KAT7 | O95251 | 1/20 | 0.46 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29894 | 0.88 | CCR4 (0.63) | CCR4KAT7KAT6BKAT6AKAT5 | |
| SCHEMBL30230 | 0.84 | CCR4 (0.71) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL18571 | 0.84 | CCR4 (0.62) | CCR4KAT7KAT6BKAT6AKAT5 | |
| SCHEMBL26339 | 0.83 | CCR4 (0.86) | CCR4KAT7KAT6BKAT6AKAT5 | |
| SCHEMBL186312 | 0.83 | CCR4 (0.56) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL356729 | 0.82 | CCR4 (0.73) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL12473981 | 0.81 | CCR4 (0.75) | CCR4KAT7KAT6BKAT6AKAT5 | |
| SCHEMBL30447 | 0.79 | CCR4 (0.74) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30317 | 0.79 | CCR4 (0.65) | CCR4KAT7KAT6BKAT6AKAT5 | |
| SCHEMBL28478 | 0.79 | CCR4 (0.65) | CCR4KAT7KAT6BKAT6AKAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025473-A1 | CC.CHEMOKINE RECEPTOR 4 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012025473-A1 | CC.CHEMOKINE RECEPTOR 4 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-03-01 | — | — | WO | disclosed |