SCHEMBL30456043

SCHEMBL30456043

CNCC(F)CCN(C)C

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.40
CARM1 Q86X55 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
PRMT1 Q99873 1/20 0.40
PRMT8 Q9NR22 1/20 0.40
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20083652 0.74
SCHEMBL26042762 0.74
SCHEMBL29318832 0.74
SCHEMBL23969445 0.73 PRMT3 (0.42) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL26042766 0.72
SCHEMBL24187705 0.72
SCHEMBL26042844 0.72
SCHEMBL901161 0.71 CARM1 (0.40) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL22129892 0.71 PRMT3 (0.40) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL31442725 0.71 PRMT3 (0.40) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023116761-A1 PYRIMIDINE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE 英矽智能科技知识产权有限公司 2023-06-29 WO disclosed