SCHEMBL901161

SCHEMBL901161

CNCC(O)CCN(C)C

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 3/20 0.40
PRMT3 O60678 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
PRMT1 Q99873 1/20 0.40
PRMT8 Q9NR22 1/20 0.40
KISS1R Q969F8 2/20 0.34
KDM4E B2RXH2 2/20 0.33
MAPT P10636 1/20 0.32
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31
ALOX15 P16050 1/20 0.31
SLC6A2 P23975 2/20 0.30
SLC6A4 P31645 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28156458 0.86 PRMT3 (0.37) CARM1PRMT3PRMT6PRMT1PRMT8
SCHEMBL2452569 0.79 MAPT (0.42) CARM1PRMT3PRMT6PRMT1PRMT8
SCHEMBL10608479 0.77 ALOX15 (0.33) CARM1KISS1RKDM4EALOX15
SCHEMBL6531597 0.75
SCHEMBL8982381 0.74 CYP2D6 (0.45) HTR2AHRH1
SCHEMBL23969445 0.73 PRMT3 (0.42) CARM1PRMT3PRMT6PRMT1PRMT8
SCHEMBL27971888 0.73 KDM4E (0.40) CARM1PRMT3PRMT6PRMT1PRMT8
SCHEMBL2246543 0.73
SCHEMBL4063929 0.72
SCHEMBL19080607 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3161029-B1 PYRROLIDINE-BASED CATALYSTS FOR USE IN POLYURETHANE MATERIALS HUNTSMAN PETROCHEMICAL LLC (US) 2023-01-11 EP claimed
CN-107743502-B Curing composition 爱客多有限公司 2020-08-28 CN claimed
US-9988483-B2 Pyrrolidine-based catalysts for use in polyurethane materials HUNTSMAN PETROCHEMICAL LLC (US) 2018-06-05 US claimed
US-9926404-B2 Curing compositions AQDOT LIMITED (GB) 2018-03-27 US claimed
EP-3095804-B1 CURING COMPOSITIONS AQDOT LTD (GB) 2017-09-27 EP claimed
EP-3161029-A1 PYRROLIDINE-BASED CATALYSTS FOR USE IN POLYURETHANE MATERIALS Huntsman Petrochemical LLC (US) 2017-05-03 EP claimed
US-20170101501-A1 PYRROLIDINE-BASED CATALYSTS FOR USE IN POLYURETHANE MATERIALS HUNTSMAN PETROCHEMICAL LLC 2017-04-13 US claimed
US-20160340467-A1 CURING COMPOSITIONS AQDOT LIMITED (GB) 2016-11-24 US claimed
EP-3095804-A1 CURING COMPOSITIONS Aqdot Ltd (GB) 2016-11-23 EP claimed
EP-2106415-B1 TERTIARY AMINES BLOCKED WITH POLYMER ACIDS HUNTSMAN PETROCHEMICAL LLC (US) 2016-04-20 EP claimed
WO-2015200408-A1 PYRROLIDINE-BASED CATALYSTS FOR USE IN POLYURETHANE MATERIALS HUNTSMAN PETROCHEMICAL LLC (US) 2015-12-30 WO claimed
US-20100099785-A1 TERTIARY AMINES BLOCKED WITH POLYMER ACIDS HUNTSMAN PETROCHEMICAL CORPORATION (US) 2010-04-22 US claimed
CN-114127144-B Transition metal chelating polyol blends for polyurethane polymers 陶氏环球技术有限责任公司 2024-11-22 CN disclosed
WO-2024132805-A1 POLYURETHANE COMPOSITE AND ARTICLE COMPRISING THE SAME BASF SE (DE) 2024-06-27 WO disclosed
US-11958935-B2 Polyurethane insulation foam composition comprising a stabilizing compound HUNTSMAN INTERNATIONAL LLC 2024-04-16 US disclosed
WO-2024054480-A1 TERTIARY AMINE CATALYST FOR POLYURETHANE FOAM HUNTSMAN PETROCHEMICAL LLC (US) 2024-03-14 WO disclosed
EP-0271822-A2 Void-free molded polyurethane articles with surface attachment strips AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-06-22 EP disclosed
US-4717611-A AUTOMOBILE SEAT COVERINGS WITH ATTACHMENT STRIPS COATED WITH A POLYVINYL ALCOHOL, DIISOCYANATE AND CATALYST MIXTURE AND CURED PRIOR TO FOAMING AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-01-05 US disclosed
US-4610819-A Process for the preparation of aromatic-1,4-oxazepinones and thiones A. H. ROBINS COMPANY, INC. (US) 1986-09-09 US disclosed
EP-0175570-A2 Process for the preparation of aromatic-1,4-oxazepinones and thiones A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) 1986-03-26 EP disclosed