SCHEMBL30456219

SCHEMBL30456219

COc1ccc2nc3cc(N)c(=O)cc-3oc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 10/20 0.66
KDM4E B2RXH2 4/20 0.63
ALDH1A1 P00352 4/20 0.63
MAPT P10636 3/20 0.63
RAB9A P51151 2/20 0.63
RECQL P46063 2/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
ALPL P05186 1/20 0.63
POLB P06746 1/20 0.63
ALPI P09923 1/20 0.63
ALPG P10696 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
CYP1A2 P05177 1/20 0.49
MAOB P27338 3/20 0.47
CYP3A4 P08684 3/20 0.46
HPGD P15428 3/20 0.46
HSD17B10 Q99714 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TP53 P04637 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3764052 1.00 APP (0.66) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL3776968 0.80 ALDH1A1 (0.68) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL28427466 0.80 MAPT (0.68) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL31115697 0.80 APP (1.00) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL563392 0.80 APP (1.00) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL3774405 0.78 APP (0.58) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL29359225 0.77 MAPT (1.00) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL2609261 0.77 MAPT (1.00) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL14415118 0.77 SNCA (0.61) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL31026258 0.76 ALDH1A1 (0.63) APPKDM4EALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023164606-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-08-31 WO claimed
EP-4661678-A1 FORMULATION FOR STABILIZATION OF BIOLOGICAL MATERIALS Indigo AG, Inc. (US) 2025-12-17 EP disclosed
WO-2024211130-A1 METHODS FOR MODIFYING MEIOTIC RECOMBINATION IN PLANTS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-10-10 WO disclosed
WO-2024168313-A1 FORMULATION FOR STABILIZATION OF BIOLOGICAL MATERIALS INDIGO AG, INC. (US) 2024-08-15 WO disclosed
WO-2024015884-A1 ENDOPHYTE COMPOSITIONS AND METHODS FOR IMPROVED PLANT HEALTH INDIGO AG, INC. (US) 2024-01-18 WO disclosed
WO-2023164606-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-08-31 WO disclosed
WO-2023108033-A2 ENDOPHYTE COMPOSITIONS AND METHODS FOR IMPROVED PLANT HEALTH INDIGO AG, INC. (US) 2023-06-15 WO disclosed