SCHEMBL3764052

SCHEMBL3764052

COc1ccc2nc3cc(N)c(=O)cc-3oc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 10/20 0.66
KDM4E B2RXH2 4/20 0.63
ALDH1A1 P00352 4/20 0.63
MAPT P10636 3/20 0.63
RAB9A P51151 2/20 0.63
RECQL P46063 2/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
ALPL P05186 1/20 0.63
POLB P06746 1/20 0.63
ALPI P09923 1/20 0.63
ALPG P10696 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
CYP1A2 P05177 1/20 0.49
MAOB P27338 3/20 0.47
CYP3A4 P08684 3/20 0.46
HPGD P15428 3/20 0.46
HSD17B10 Q99714 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TP53 P04637 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30456219 1.00 APP (0.66) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL3776968 0.80 ALDH1A1 (0.68) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL28427466 0.80 MAPT (0.68) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL31115697 0.80 APP (1.00) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL563392 0.80 APP (1.00) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL3774405 0.78 APP (0.58) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL29359225 0.77 MAPT (1.00) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL2609261 0.77 MAPT (1.00) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL14415118 0.77 SNCA (0.61) APPKDM4EALDH1A1MAPTRAB9A
SCHEMBL31026258 0.76 ALDH1A1 (0.63) APPKDM4EALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250160275-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-05-22 US claimed
WO-2023164606-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-08-31 WO claimed
WO-2009003625-A1 AMINOPHENOXAZINONE AS AN ANTI-TUMOUR AND ANTI-INFLAMMATORY AGENT EBERHARD-KARLS-UNIVERSITAET TUEBINGEN UNIVERSITAETSKILINIKUM (DE) 2009-01-08 WO claimed
US-12599139-B2 Means and methods for improving plant growth and yield APHEA.BIO NV (BE) 2026-04-14 US disclosed
US-20260013509-A1 ENDOPHYTE COMPOSITIONS AND METHODS FOR IMPROVED PLANT HEALTH INDIGO AG INC (US) 2026-01-15 US disclosed
US-20250378507-A1 MACHINE LEARNING IN AGRICULTURAL PLANTING, GROWING, AND HARVESTING CONTEXTS INDIGO AG INC (US) 2025-12-11 US disclosed
US-20250351831-A1 ENDOPHYTE COMPOSITIONS AND METHODS FOR IMPROVED PLANT HEALTH INDIGO AG INC (US) 2025-11-20 US disclosed
EP-4456713-B1 PRODUCTS AND METHODS FOR IMPROVING PLANT GROWTH FEATURES APHEA BIO NV (BE) 2025-11-12 EP disclosed
EP-4642234-A1 PRODUCTS AND METHODS FOR PATHOGEN CONTROL IN PLANTS Aphea.Bio NV (BE) 2025-11-05 EP disclosed
EP-4637325-A1 PRODUCTS AND METHODS FOR IMPROVING PLANT GROWTH FEATURES Aphea.Bio NV (BE) 2025-10-29 EP disclosed
EP-4637360-A1 PRODUCTS AND METHODS FOR IMPROVING PLANT GROWTH FEATURES Aphea.Bio NV (BE) 2025-10-29 EP disclosed
WO-2018160245-A1 ENDOPHYTE COMPOSITIONS AND METHODS FOR IMPROVEMENT OF PLANT TRAITS INDIGO AG, INC. (US) 2018-09-07 WO disclosed
WO-2018160244-A1 ENDOPHYTE COMPOSITIONS AND METHODS FOR IMPROVEMENT OF PLANT TRAITS INDIGO AG, INC. (US) 2018-09-07 WO disclosed
US-20180251776-A1 ENDOPHYTE COMPOSITIONS AND METHODS FOR IMPROVEMENT OF PLANT TRAITS INDIGO AGRICULTURE, INC. 2018-09-06 US disclosed
US-20180249716-A1 ENDOPHYTE COMPOSITIONS AND THE METHODS FOR IMPROVEMENT OF PLANT TRAITS INDIGO AGRICULTURE, INC. 2018-09-06 US disclosed
WO-2018102733-A1 MODULATED NUTRITIONAL QUALITY TRAITS IN SEEDS INDIGO AG, INC. (US) 2018-06-07 WO disclosed
US-20180153174-A1 MODULATED NUTRITIONAL QUALITY TRAITS IN SEEDS INDIGO AG, INC. 2018-06-07 US disclosed
US-20100324285-A1 ANTIINFLAMMATORY AGENT COMPRISING 2-AMINOPHENOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2010-12-23 US disclosed
EP-2098228-A1 ANTIINFLAMMATORY AGENT COMPRISING 2-AMINOPHENOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2009-09-09 EP disclosed
WO-2009003625-A1 AMINOPHENOXAZINONE AS AN ANTI-TUMOUR AND ANTI-INFLAMMATORY AGENT EBERHARD-KARLS-UNIVERSITAET TUEBINGEN UNIVERSITAETSKILINIKUM (DE) 2009-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324285-A1 ANTIINFLAMMATORY AGENT COMPRISING 2-AMINOPHENOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT PTGES2, PTGS2, PTGES APP 920/4885KDM4E 1347/4885ALDH1A1 535/4885
US-20260013509-A1 ENDOPHYTE COMPOSITIONS AND METHODS FOR IMPROVED PLANT HEALTH NOS2, MAFG, NOP2 APP 3533/4885KDM4E 2272/4885ALDH1A1 4325/4885
US-12599139-B2 Means and methods for improving plant growth and yield RNGTT, FBL, NOP2 APP 1872/4885KDM4E 571/4885ALDH1A1 4707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.