Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24309342 | 0.86 | ALDH1A1 (0.40) | ALDH1A1MAPTRAB9ANPSR1CHRM5 | |
| SCHEMBL30456400 | 0.81 | NLRP3 (0.34) | ALDH1A1MAPTRAB9ANPSR1MTOR | |
| SCHEMBL30457542 | 0.75 | CHRM5 (0.33) | ALDH1A1MAPTRAB9ANPSR1CHRM5 | |
| SCHEMBL1501094 | 0.71 | GAA (0.41) | ALDH1A1MAPTRAB9ANPSR1CHRM5 | |
| SCHEMBL30456708 | 0.70 | ALDH1A1 (0.32) | ALDH1A1MAPTRAB9ANPSR1MTOR | |
| SCHEMBL9202916 | 0.69 | ALDH1A1 (0.39) | ALDH1A1MAPTRAB9ANPSR1CHRM5 | |
| SCHEMBL22531650 | 0.69 | ALDH1A1 (0.36) | ALDH1A1MAPTRAB9ANPSR1MTOR | |
| SCHEMBL25240029 | 0.69 | MTOR (0.39) | ALDH1A1MAPTRAB9ANPSR1MTOR | |
| SCHEMBL30456207 | 0.67 | ALDH1A1 (0.33) | ALDH1A1MAPTRAB9ANPSR1MTOR | |
| SCHEMBL25236041 | 0.67 | ALDH1A1 (0.32) | ALDH1A1MAPTRAB9ANPSR1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | VANDERBILT UNIVERSITY | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | CHRM5, CHRM1, CHRM2 | ALDH1A1 622/4885MAPT 2286/4885RAB9A 1907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.