Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2583175 | 0.71 | DYRK1A (0.49) | JAK2HTTSMN1; SMN2DYRK1AFLT1 | |
| SCHEMBL14006680 | 0.70 | PIK3CD (0.49) | ADRA2CPIK3CDPIK3CAPIK3CBPOLB | |
| SCHEMBL25379635 | 0.70 | EPHB4 (0.46) | ADRA2CPOLBL3MBTL1 | |
| SCHEMBL21628161 | 0.67 | PI4KB (0.49) | ADRA2CPI4KB | |
| SCHEMBL30457108 | 0.66 | BRD4 (0.48) | POLBKMT2ASMN1; SMN2NPSR1PI4KB | |
| SCHEMBL3970342 | 0.65 | KDM4E (0.52) | KMT2AL3MBTL1HTTSMN1; SMN2DYRK1A | |
| SCHEMBL14006689 | 0.65 | EPHB4 (0.46) | ADRA2CKMT2AL3MBTL1GSK3AGSK3B | |
| SCHEMBL14006673 | 0.65 | L3MBTL1 (0.47) | ADRA2CEGFRPOLBKMT2AL3MBTL1 | |
| SCHEMBL3968151 | 0.63 | ALDH1A1 (0.40) | HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL20528869 | 0.62 | ALDH1A1 (0.42) | KMT2AL3MBTL1SMN1; SMN2DYRK1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864017-B1 | 2,6-DIMETHYL-N-((PYRIDIN-4-YL)METHYL)IMIDAZO[1,2-B]PYRIDAZIN-8-AMINE AND 2,5-DIMETHYL-N-[(PYRIDIN-4-YL)METHYL]PYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE DERIVATIVES FOR TREATING VIRAL INFECTIONS | CUROVIR AB (SE) | 2023-07-26 | — | — | EP | disclosed |
| EP-3864017-C0 | 2,6-DIMETHYL-N-((PYRIDIN-4-YL)METHYL)IMIDAZO[1,2-B]PYRIDAZIN-8-AMINE AND 2,5-DIMETHYL-N-[(PYRIDIN-4-YL)METHYL]PYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE DERIVATIVES FOR TREATING VIRAL INFECTIONS | CUROVIR AB (SE) | 2023-07-26 | — | — | EP | disclosed |