Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18655858 | 0.85 | CTSK (0.42) | CTSKBTKDRD2KCNA3CA1 | |
| SCHEMBL18655405 | 0.83 | CTSK (0.44) | CTSKBTKDRD2KCNA3CA1 | |
| SCHEMBL30164348 | 0.81 | CTSK (0.47) | CTSKBTKDRD2KCNA3CA1 | |
| SCHEMBL3108831 | 0.79 | KCNA3 (0.56) | CTSKBTKDRD2KCNA3CA1 | |
| SCHEMBL25280025 | 0.78 | WNT1 (0.35) | — | |
| SCHEMBL27172421 | 0.77 | CTSK (0.43) | CTSKBTKCA1CA2HSD11B1 | |
| SCHEMBL25497247 | 0.77 | EPHX1 (0.43) | CTSKBTKCA1CA2HSD11B1 | |
| SCHEMBL1700413 | 0.77 | CTSK (0.56) | CTSKBTKDRD2KCNA3CA1 | |
| SCHEMBL1810659 | 0.77 | CTSK (0.56) | CTSKBTKDRD2KCNA3CA1 | |
| SCHEMBL1700415 | 0.77 | CTSK (0.56) | CTSKBTKDRD2KCNA3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110700-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-06-22 | — | — | WO | disclosed |