Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.50 |
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PAK4 | O96013 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | GRK5 | P34947 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15698921 | 0.87 | PTPN2 (0.49) | DYRK1APIM1GSK3AGSK3BCDK5 | |
| SCHEMBL30568673 | 0.87 | PTPN2 (0.49) | DYRK1APIM1GSK3AGSK3BCDK5 | |
| SCHEMBL120469 | 0.85 | BCL2L1 (0.54) | DYRK1APIM1PTPN2CHRNA7MGLL | |
| SCHEMBL31262807 | 0.85 | BCL2L1 (0.54) | DYRK1APIM1PTPN2CHRNA7MGLL | |
| SCHEMBL147472 | 0.84 | CHRNA7 (0.48) | DYRK1ACHRNA7MGLLEPHX2SCN4A | |
| SCHEMBL4654119 | 0.80 | HDAC1 (0.52) | DYRK1APTPN2CHRNA7CES2PPARA | |
| SCHEMBL21361764 | 0.77 | CHRNA7 (0.46) | DYRK1ACHRNA7MGLLEPHX2SCN4A | |
| SCHEMBL3580021 | 0.77 | BCL2L1 (0.49) | DYRK1APIM1GSK3AGSK3BCDK5 | |
| SCHEMBL3613052 | 0.77 | PTPN2 (0.55) | PTPN2CHRNA7HDAC3HDAC4HDAC1 | |
| SCHEMBL901372 | 0.77 | CHRNA7 (0.43) | DYRK1ACHRNA7MGLLEPHX2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448508-A1 | BENZOTHIOPHENE DERIVATIVES AS RXFP1 AGONISTS | Bristol-Myers Squibb Company (US) | 2024-10-23 | — | — | EP | disclosed |
| CN-118647606-A | Benzothiophene derivatives as RXFP1 agonists | 百时美施贵宝公司 | 2024-09-13 | — | — | CN | disclosed |
| WO-2023114823-A1 | BENZOTHIOPHENE DERIVATIVES AS RXFP1 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |