SCHEMBL120469

SCHEMBL120469

O=C(O)c1cc2ccc(C(F)(F)F)cc2s1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.54
GPR35 Q9HC97 2/20 0.50
CHRNA7 P36544 1/20 0.49
PTPN2 P17706 2/20 0.48
PPARA Q07869 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
DYRK1A Q13627 2/20 0.43
DAO P14920 1/20 0.43
TBXAS1 P24557 1/20 0.43
PIM1 P11309 1/20 0.43
PIM2 Q9P1W9 1/20 0.43
CES2 O00748 2/20 0.42
EPHX2 P34913 1/20 0.41
SCN4A P35499 1/20 0.41
MGLL Q99685 1/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC3 O15379 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31262807 1.00 BCL2L1 (0.54) BCL2L1GPR35CHRNA7PTPN2PPARA
SCHEMBL153428 0.87 BCL2L1 (0.54) BCL2L1GPR35CHRNA7PTPN2PPARA
SCHEMBL147472 0.85 CHRNA7 (0.48) BCL2L1CHRNA7PPARADYRK1ACES2
SCHEMBL30456961 0.85 DYRK1A (0.50) CHRNA7PTPN2PPARAKDM4EALDH1A1
SCHEMBL4654119 0.84 HDAC1 (0.52) CHRNA7PTPN2PPARAKDM4EALDH1A1
SCHEMBL3580021 0.84 BCL2L1 (0.49) BCL2L1GPR35CHRNA7PTPN2DYRK1A
SCHEMBL3573988 0.82 BCL2L1 (0.46) BCL2L1GPR35CHRNA7PTPN2PPARA
SCHEMBL3562083 0.80 BCL2L1 (0.51) BCL2L1GPR35CHRNA7PTPN2TBXAS1
Isopropylamine SCHEMBL13735900 0.79 BCL2L1 (0.46) BCL2L1GPR35CHRNA7PTPN2PPARA
SCHEMBL15697513 0.79 PPARA (0.57) PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US claimed
US-9232792-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-01-12 US claimed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US claimed
EP-2926660-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-10-07 EP claimed
EP-2706850-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company, Limited (JP) 2014-03-19 EP claimed
US-20140031233-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-30 US claimed
WO-2012153861-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-15 WO claimed
EP-2167077-A2 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR Bayer Schering Pharma Aktiengesellschaft (DE) 2010-03-31 EP claimed
US-20090023741-A1 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR BAYER SCHERING PHARMA AG (DE) 2009-01-22 US claimed
WO-2008152099-A2 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-12-18 WO claimed
US-20040259930-A1 Linear basic compounds having nk-2 antagonist activity and formulations thereof MALESCI INSTITUTO FARMACOBIOLOGICO S.P.A. (IT) 2004-12-23 US claimed
US-12583849-B2 KCNT1 inhibitors and methods of use PRAXIS PRECISION MEDICINES, INC. (US) 2026-03-24 US disclosed
US-20260049060-A1 TETRAHYDROISOQUINOLINYLMETHYLBENZAMIDE COMPOUNDS NATIONAL HEALTH RES INST (TW) 2026-02-19 US disclosed
EP-4692069-A2 KCNT1 INHIBITORS AND METHODS OF USE Praxis Precision Medicines, Inc. (US) 2026-02-11 EP disclosed
EP-4110317-B1 KCNT1 INHIBITORS AND METHODS OF USE PRAXIS PREC MEDICINES INC (US) 2025-11-19 EP disclosed
WO-2005077926-A2 BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES USEFUL FOR THE TREATMENT OF CARDIOVASCULAR DISEASE SMITHKLINE BEECHAM CORPORATION (US) 2005-08-25 WO disclosed
WO-2005070885-A1 BIS BICYCLIC AMIDES AS VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS OF INFLAMMATORY AND NEUROPATIC PAIN AMGEN INC. (US) 2005-08-04 WO disclosed
US-20050165046-A1 Vanilloid receptor ligands and their use in treatments AMGEN, INC. 2005-07-28 US disclosed
US-20050165049-A1 Vanilloid receptor ligands and their use in treatments AMGEN, INC. 2005-07-28 US disclosed
US-20040259930-A1 Linear basic compounds having nk-2 antagonist activity and formulations thereof MALESCI INSTITUTO FARMACOBIOLOGICO S.P.A. (IT) 2004-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583849-B2 KCNT1 inhibitors and methods of use KCNT1, SCN1A, KCNT2 BCL2L1 1359/4885GPR35 2308/4885CHRNA7 132/4885
US-20260049060-A1 TETRAHYDROISOQUINOLINYLMETHYLBENZAMIDE COMPOUNDS OPRK1, OPRD1, OPRM1 BCL2L1 2656/4885GPR35 648/4885CHRNA7 255/4885
US-20050165049-A1 Vanilloid receptor ligands and their use in treatments TRPV1, TRPV2, TRPV3 BCL2L1 632/4885GPR35 55/4885CHRNA7 418/4885
US-20050165046-A1 Vanilloid receptor ligands and their use in treatments TRPV1, TRPV2, TRPV3 BCL2L1 753/4885GPR35 40/4885CHRNA7 377/4885
US-20140031233-A1 METHOD FOR PROMOTING PLANT GROWTH MYB, GRHPR, HACL2 BCL2L1 1455/4885GPR35 4429/4885CHRNA7 4600/4885
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B BCL2L1 2137/4885GPR35 3997/4885CHRNA7 4781/4885
US-20090023741-A1 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR PTGER2, PTGER1, PTGDR2 BCL2L1 3789/4885GPR35 60/4885CHRNA7 1077/4885
US-20040259930-A1 Linear basic compounds having nk-2 antagonist activity and formulations thereof BDKRB2, BDKRB1, TACR2 BCL2L1 2632/4885GPR35 674/4885CHRNA7 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.