⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL8311625 | 0.92 | NPC1 (0.32) | — | |
| SCHEMBL17899451 | 0.80 | — | — | |
| SCHEMBL79434 | 0.79 | — | — | |
| SCHEMBL2865670 | 0.78 | — | — | |
| SCHEMBL8788251 | 0.78 | — | — | |
| SCHEMBL8788253 | 0.78 | — | — | |
| SCHEMBL16559351 | 0.78 | CA12 (0.32) | — | |
| SCHEMBL681184 | 0.75 | ELANE (0.34) | — | |
| Ethylene Glycol Diisobutanoate SCHEMBL843146 | 0.75 | TSHR (0.36) | — | |
| SCHEMBL3076658 | 0.74 | CA2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925640-B | ((3-Carbamoyl-5-fluoropyrazin-2-yl) oxy) methyl isobutyrate and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2025-03-28 | — | — | CN | claimed |
| CN-115925640-A | ((3-carbamoyl-5-fluoropyrazin-2-yl) oxy) methyl isobutyrate and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-04-07 | — | — | CN | claimed |
| US-9359376-B2 | Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds | SPHAERA PHARMA PTE. LTD (SG) | 2016-06-07 | — | — | US | claimed |
| US-20140121367-A1 | SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS | PIVOT HOLDING LLC | 2014-05-01 | — | — | US | claimed |
| EP-2693876-A1 | SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS | Sphaera Pharma Pte. Ltd (SG) | 2014-02-12 | — | — | EP | claimed |
| WO-2012137225-A1 | SUBSTITUTED METHYLFORMYL REAGENTS AND METHOD OF USING SAME TO MODIFY PHYSICOCHEMICAL AND/OR PHARMACOKINETIC PROPERTIES OF COMPOUNDS | SPHAERA PHARMA PVT. LTD (IN) | 2012-10-11 | — | — | WO | claimed |
| CN-122079989-A | Diazabicyclo beta-lactamase inhibitor and application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| US-20260115175-A1 | NICORANDIL DERIVATIVES | UNICYCIVE THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| EP-3937938-B1 | NICORANDIL DERIVATIVES | UNICYCIVE THERAPEUTICS INC (US) | 2026-01-28 | — | — | EP | disclosed |
| US-12396989-B2 | Nicorandil derivatives | UNICYCIVE THERAPEUTICS, INC. (US) | 2025-08-26 | — | — | US | disclosed |
| US-12377082-B2 | Nicorandil derivatives | Unicycive Therapeutics Inc. (US) | 2025-08-05 | — | — | US | disclosed |
| US-20250215030-A1 | STAT MODULATORS AND USES THEREOF | RECLUDIX PHARMA, INC. | 2025-07-03 | — | — | US | disclosed |
| US-20250215029-A1 | STAT MODULATORS AND USES THEREOF | RECLUDIX PHARMA, INC. | 2025-07-03 | — | — | US | disclosed |
| US-4487927-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| EP-0123024-A2 | 7-Acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |
| US-4463002-A | Syn-isomers of 7-substituted-3-cephem-4-carboxylic acid esters | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | disclosed |
| US-4423213-A | ANTIBIOTIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-12-27 | — | — | US | disclosed |
| US-4409214-A | Including cefixime; antibiotics | FUJISAWA PHARMACEUTICAL, CO., LTD. (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0065745-A2 | Syn-isomers of 7-substituted-3-cephem-4-carboxylic acid esters, and a process for production thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |
| EP-0030630-A2 | 7-Acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-24 | — | — | EP | disclosed |