Sugi Predict

Sugi Predict / Compounds / SCHEMBL681184

SCHEMBL681184

SCHEMBL681184

CC(C)C(=O)OCOC(=O)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.34
▸ ALDH1A1 P00352 5/20 0.33
▸ TSHR P16473 3/20 0.33
▸ MAPT P10636 2/20 0.32
▸ NPC1 O15118 2/20 0.32
▸ ALOX15 P16050 2/20 0.32
▸ POLB P06746 1/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ TDP1 Q9NUW8 2/20 0.32
▸ LMNA P02545 2/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ COMT P21964 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8560408 0.91 TSHR (0.34) ELANEALDH1A1TSHRMAPTNPC1
SCHEMBL217246 0.91 ALDH1A1 (0.41) ELANEALDH1A1TSHRMAPTNPC1
SCHEMBL217247 0.89 TSHR (0.33) ELANEALDH1A1TSHRMAPTNPC1
SCHEMBL7606317 0.89 ALDH1A1 (0.43) ALDH1A1TSHRMAPTALOX15SMN1; SMN2
SCHEMBL11631362 0.88 ELANE (0.32) ELANEALDH1A1TSHRMAPTNPC1
SCHEMBL6066229 0.87 ALOX15 (0.46) TSHRMAPTALOX15SMN1; SMN2TDP1
SCHEMBL22799098 0.87 GRIN2D (0.37) LMNA
SCHEMBL7370005 0.87 ALDH1A1 (0.32) ALDH1A1MAPTNPC1POLB
SCHEMBL12044962 0.87 NAAA (0.41) ALDH1A1MAPTALOX15TDP1LMNA
SCHEMBL1815860 0.87 NPC1 (0.32) ALDH1A1NPC1COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3994929-A Production of 2,2-disubstituted propiolactones EASTMAN KODAK COMPANY (US) 1976-11-30 — — US claimed
US-12637481-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2026-05-26 — — US disclosed
US-20230348452-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-11-02 — — US disclosed
US-20230301988-A1 INHIBITORS OF SARS COV-2 INFECTION AND USES THEREOF THE TEXAS A&M UNIVERSITY SYSTEM 2023-09-28 — — US disclosed
US-20230151029-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF QPEX BIOPHARMA, INC. 2023-05-18 — — US disclosed
CN-116034109-A Boric acid derivatives and therapeutic uses thereof QPEX生物制药有限公司 2023-04-28 — — CN disclosed
EP-4121433-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF QPEX BIOPHARMA, INC. (US) 2023-01-25 — — EP disclosed
WO-2021188700-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF QPEX BIOPHARMA, INC. (US) 2021-09-23 — — WO disclosed
US-20180362485-A1 N-HYDROXYFORMAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THEM FOR USE AS BMP l, TLL1 AND/OR TLL2 INHIBITORS GLAXOSMITHKLINE IP NO 2 LTD (GB) 2018-12-20 — — US disclosed
US-9943609-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2018-04-17 — — US disclosed
US-7179865-B2 Purification with reducing agents of vinyl polymers obtained by atom transfer radical polymerization KANEKA CORPORATION (JP) 2007-02-20 — — US disclosed
US-20070004874-A1 Polymer and epoxy resin compositions KANEKA CORPORATION (JP) 2007-01-04 — — US disclosed
US-20070004880-A1 Polymer, process for producing the polymer, and curable composition containing the polymer KANEKA CORPORATION (JP) 2007-01-04 — — US disclosed
EP-0120257-B1 PROCESS FOR THE PREPARATION OF ISOCHROMAN DERIVATIVES HAARMANN & REIMER GMBH (DE) 1986-12-17 — — EP disclosed
US-4523023-A Preparation of isochromane derivatives HAARMANN & REIMER GMBH (DE) 1985-06-11 — — US disclosed
EP-0120257-A1 Process for the preparation of isochroman derivatives HAARMANN & REIMER GMBH (DE) 1984-10-03 — — EP disclosed
US-4123552-A FUNGICIDES CHEVRON RESEARCH COMPANY (US) 1978-10-31 — — US disclosed
US-4012526-A Oxymethylene di-carboxylic acid esters as anti-fungal agents and animal growth promoters CHEVRON RESEARCH COMPANY (US) 1977-03-15 — — US disclosed
US-3994929-A Production of 2,2-disubstituted propiolactones EASTMAN KODAK COMPANY (US) 1976-11-30 — — US disclosed
US-3931412-A Fungus and bacteria control with di-carboxylic acid esters CHEVRON RESEARCH COMPANY (US) 1976-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151029-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF BLVRB, BLK, BTD ELANE 314/4885ALDH1A1 755/4885TSHR 3055/4885
US-20230348452-A1 COMPOUNDS AND USES THEREOF VHL, CLN6, BRCA1 ELANE 1373/4885ALDH1A1 2600/4885TSHR 4245/4885
US-12637481-B2 Boronic acid derivatives and therapeutic uses thereof BBC3, BLK, BRI3BP ELANE 938/4885ALDH1A1 2203/4885TSHR 1738/4885
US-20230301988-A1 INHIBITORS OF SARS COV-2 INFECTION AND USES THEREOF CTSV, ACE2, CTSL ELANE 520/4885ALDH1A1 2648/4885TSHR 4768/4885
US-20180362485-A1 N-HYDROXYFORMAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THEM FOR USE AS BMP l, TLL1 AND/OR TLL2 INHIBITORS BMP1, BMP2, BMPR1A ELANE 732/4885ALDH1A1 1485/4885TSHR 2174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.