Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.43 |
| ▸ | SORD | Q00796 | 16/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25236876 | 1.00 | EIF2AK4 (0.43) | EIF2AK4SORDHRH4NMT1 | |
| SCHEMBL6294832 | 0.85 | EIF2AK4 (0.43) | EIF2AK4SORDHRH4NMT1 | |
| SCHEMBL3536634 | 0.80 | HRH3 (0.55) | EIF2AK4SORDHRH4 | |
| SCHEMBL3536631 | 0.80 | HRH3 (0.55) | EIF2AK4SORDHRH4 | |
| SCHEMBL25234344 | 0.75 | PTPN11 (0.38) | EIF2AK4 | |
| SCHEMBL25240554 | 0.73 | PTPN11 (0.43) | EIF2AK4SORD | |
| SCHEMBL30457411 | 0.73 | PTPN11 (0.43) | EIF2AK4SORD | |
| SCHEMBL6293205 | 0.72 | SORD (0.39) | EIF2AK4SORDNMT1 | |
| SCHEMBL6294679 | 0.72 | EIF2AK4 (0.42) | EIF2AK4SORDHRH4NMT1 | |
| SCHEMBL23744756 | 0.72 | EIF2AK4 (0.39) | EIF2AK4SORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110843-A1 | HETEROBICYCLIC DERIVATIVES AS ITK INHIBITORS | ALMIRALL, S.A. (ES) | 2023-06-22 | — | — | WO | disclosed |