SCHEMBL30457634

SCHEMBL30457634

C#CC(OC(=O)OC(C)(C)C)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSK P43235 4/20 0.40
CTSS P25774 3/20 0.40
ATM Q13315 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KMT2A Q03164 1/20 0.35
ELANE P08246 1/20 0.35
ALDH1A1 P00352 2/20 0.34
CYP3A4 P08684 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
HTT P42858 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
RIPK1 Q13546 1/20 0.33
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11513632 0.86 CTSK (0.41) CTSKCTSSATML3MBTL1KMT2A
SCHEMBL29040565 0.85 CYP2D6 (0.40) L3MBTL1KMT2AALDH1A1CYP3A4TDP1
SCHEMBL31238799 0.83 KMT2A (0.47) KMT2AALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL18367774 0.78 ALDH1A1 (0.50) KMT2AALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL2558349 0.78 ALDH1A1 (0.42) CTSKCTSSATML3MBTL1KMT2A
SCHEMBL372279 0.78 HDAC4 (0.39) KMT2AALDH1A1
SCHEMBL27780418 0.78 CYP2D6 (0.40) L3MBTL1KMT2AALDH1A1CYP3A4TDP1
SCHEMBL18206556 0.77 ALDH1A1 (0.45) CTSKCTSSATML3MBTL1KMT2A
SCHEMBL18206009 0.77 ALDH1A1 (0.45) CTSKCTSSATML3MBTL1KMT2A
SCHEMBL11796175 0.77 ALDH1A1 (0.45) CTSKCTSSATML3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444370-A Preparation method of alpha, beta-unsaturated carboxylic acid derivative 大连理工常熟研究院有限公司 2023-07-18 CN disclosed