Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140881 | 0.90 | ADRB2 (0.50) | ADRB2ADRB1ADRB3MAPTALDH1A1 | |
| SCHEMBL5366418 | 0.87 | ADRB2 (0.38) | ADRB2ADRB1ADRB3MAPTTSHR | |
| SCHEMBL13957054 | 0.86 | ADRB2 (0.50) | ADRB2ADRB1ADRB3MAPTTSHR | |
| SCHEMBL1296760 | 0.86 | CYP3A4 (0.58) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL10523965 | 0.86 | CYP3A4 (0.58) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL5363380 | 0.85 | ADRB2 (0.42) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL22856002 | 0.84 | CYP3A4 (0.53) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL1297165 | 0.82 | CYP3A4 (0.58) | MAPTTSHRCYP3A4ATMTDP1 | |
| SCHEMBL30368993 | 0.82 | ADRB2 (0.53) | ADRB2ADRB1ADRB3MAPTALDH1A1 | |
| SCHEMBL14199959 | 0.82 | ADRB2 (0.53) | ADRB2ADRB1ADRB3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194144-A | Prodrugs of phosphoramide nucleotide analogs and pharmaceutical uses thereof | 吉利德科学公司 | 2023-05-30 | — | — | CN | disclosed |