Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20571450 | 1.00 | FAAH (0.34) | FAAHSCDGPR119MGLLPIK3CD | |
| SCHEMBL21896221 | 0.85 | MGLL (0.38) | FAAHSCDGPR119MGLL | |
| SCHEMBL30457967 | 0.84 | SCD (0.42) | SCDMGLLNOTUM | |
| SCHEMBL20570672 | 0.84 | SCD (0.42) | SCDMGLLNOTUM | |
| SCHEMBL21821100 | 0.82 | FAAH (0.37) | FAAHSCDGPR119MGLLHRH3 | |
| SCHEMBL31168748 | 0.82 | FAAH (0.37) | FAAHSCDGPR119MGLLHRH3 | |
| SCHEMBL31168779 | 0.82 | FAAH (0.40) | FAAHMGLL | |
| SCHEMBL21821098 | 0.82 | FAAH (0.40) | FAAHMGLL | |
| SCHEMBL31168830 | 0.81 | PIK3CD (0.38) | FAAHGPR119MGLLPIK3CDPIK3CA | |
| SCHEMBL21821078 | 0.81 | PIK3CD (0.38) | FAAHGPR119MGLLPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678177-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-06-13 | — | — | CN | disclosed |