SCHEMBL30457989

SCHEMBL30457989

Brc1ccc2c(-c3cccc4cc(Br)ccc34)cccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.52
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
RXFP1 Q9HBX9 1/20 0.42
MAPK1 P28482 3/20 0.41
CYP1A2 P05177 3/20 0.41
ERN1 O75460 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
DAO P14920 1/20 0.40
ALDH1A1 P00352 3/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
CASP1 P29466 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PTPRC P08575 1/20 0.39
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6129310 1.00 CYP2A6 (0.52) CYP2A6MEN1KMT2ARXFP1MAPK1
SCHEMBL18529228 0.87 CYP2A6 (0.45) CYP2A6MEN1KMT2ARXFP1MAPK1
SCHEMBL21203632 0.86 CYP2A6 (0.48) CYP2A6MEN1KMT2ARXFP1MAPK1
SCHEMBL28502668 0.82 ALDH1A1 (0.48) CYP2A6MEN1KMT2ARXFP1MAPK1
SCHEMBL28247035 0.81 TLR8 (0.53) CYP2A6MEN1KMT2AALDH1A1HPGD
SCHEMBL30366175 0.81 CYP2A6 (0.52) CYP2A6MEN1KMT2ARXFP1MAPK1
SCHEMBL1461517 0.81 CYP2A6 (0.52) CYP2A6MEN1KMT2ARXFP1MAPK1
SCHEMBL29656897 0.81 CYP2A6 (0.52) CYP2A6MEN1KMT2ARXFP1MAPK1
SCHEMBL29418249 0.80 KDM4E (0.46) CYP2A6MAPK1CYP1A2NPSR1ALDH1A1
SCHEMBL18529231 0.80 CYP2A6 (0.39) CYP2A6MEN1KMT2ARXFP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303011-B Organic compound, light emitting diode having the same, and light emitting device 乐金显示有限公司 2023-06-16 CN disclosed