Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25283055 | 1.00 | TP53 (0.45) | TP53ALDH1A1RECQLPOLBPDE4A | |
| SCHEMBL6272011 | 0.86 | TP53 (0.52) | TP53POLBPDE4APDE4BPDE4C | |
| SCHEMBL2866307 | 0.82 | BPTF (0.55) | TP53ALDH1A1POLBPDE4APDE4B | |
| SCHEMBL25234663 | 0.82 | ALDH1A1 (0.42) | TP53ALDH1A1RECQLPOLBTSHR | |
| SCHEMBL30457891 | 0.82 | ALDH1A1 (0.42) | TP53ALDH1A1RECQLPOLBTSHR | |
| SCHEMBL6269927 | 0.78 | LMNA (0.54) | TP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL26106082 | 0.76 | PTPN1 (0.48) | ALDH1A1L3MBTL1 | |
| SCHEMBL26512951 | 0.76 | PTPN1 (0.48) | ALDH1A1L3MBTL1 | |
| SCHEMBL9031761 | 0.76 | TSHR (0.55) | ALDH1A1RECQLTSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL20574134 | 0.75 | CYP17A1 (0.44) | TP53ALDH1A1POLBBPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448500-A1 | BENZOTHIAZOLE, BENZOISOXAZOLE AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS | Bristol-Myers Squibb Company (US) | 2024-10-23 | — | — | EP | disclosed |
| CN-118401502-A | Benzothiazole, benzisoxazole and benzodioxole analogs as RXFP1 receptor agonists | 百时美施贵宝公司 | 2024-07-26 | — | — | CN | disclosed |
| WO-2023114822-A1 | BENZOTHIAZOLE, BENZOISOXAZOLE AND BENZODIOXOLE ANALOGS AS RXFP1 RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |