Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.57 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.49 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570710 | 1.00 | FAAH (0.57) | FAAHMGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL20571312 | 0.91 | FAAH (0.52) | FAAHMGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL31168842 | 0.91 | FAAH (0.52) | FAAHMGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL21896123 | 0.86 | FAAH (0.53) | FAAHMGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL21896151 | 0.84 | FAAH (0.57) | FAAHMGLLCYP3A4CYP2D6TSHR | |
| SCHEMBL21896137 | 0.84 | MGLL (0.46) | FAAHMGLL | |
| SCHEMBL21821118 | 0.82 | FAAH (0.43) | FAAHMGLL | |
| SCHEMBL31168819 | 0.82 | FAAH (0.43) | FAAHMGLL | |
| SCHEMBL21821182 | 0.77 | FAAH (0.62) | FAAHMGLL | |
| SCHEMBL31168783 | 0.77 | FAAH (0.62) | FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678177-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-06-13 | — | — | CN | disclosed |