SCHEMBL30458558

SCHEMBL30458558

CC(C)(C)OC(=O)n1cc(CCl)c2cccnc21

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ELANE P08246 15/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
POLB P06746 1/20 0.42
DTYMK P23919 1/20 0.41
BRD4 O60885 1/20 0.40
HTR6 P50406 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1267232 1.00 ELANE (0.46) ELANEL3MBTL1POLBDTYMKBRD4
SCHEMBL30940044 0.90 L3MBTL1 (0.47) ELANEL3MBTL1POLBDTYMKBRD4
SCHEMBL3705482 0.90 L3MBTL1 (0.47) ELANEL3MBTL1POLBDTYMKBRD4
SCHEMBL4569771 0.90 L3MBTL1 (0.50) ELANEL3MBTL1POLBDTYMKBRD4
SCHEMBL4572234 0.87 L3MBTL1 (0.46) ELANEL3MBTL1POLBDTYMKBRD4
SCHEMBL3757166 0.85 ELANE (0.43) ELANEL3MBTL1POLBDTYMKBRD4
SCHEMBL3762275 0.85 ELANE (0.47) ELANEL3MBTL1POLBDTYMKBRD4
SCHEMBL4192135 0.84 L3MBTL1 (0.54) ELANEL3MBTL1POLBDTYMKBRD4
SCHEMBL30711710 0.83 ELANE (0.55) ELANEL3MBTL1POLBDTYMK
SCHEMBL1457357 0.82 HSP90AA1 (0.37) ELANEL3MBTL1POLBBRD4HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4408845-A1 NOVEL COMPOUNDS Sitryx Therapeutics Limited (GB) 2024-08-07 EP disclosed
WO-2023052783-A1 NOVEL COMPOUNDS SITRYX THERAPEUTICS LIMITED (GB) 2023-04-06 WO disclosed