Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 9/20 | 0.41 |
| ▸ | DTYMK | P23919 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940044 | 0.86 | L3MBTL1 (0.47) | L3MBTL1ELANEDTYMKBRD4POLB | |
| SCHEMBL4569771 | 0.86 | L3MBTL1 (0.50) | L3MBTL1ELANEDTYMKBRD4POLB | |
| SCHEMBL3705482 | 0.86 | L3MBTL1 (0.47) | L3MBTL1ELANEDTYMKBRD4POLB | |
| SCHEMBL30458558 | 0.84 | ELANE (0.46) | L3MBTL1ELANEDTYMKBRD4POLB | |
| SCHEMBL4572234 | 0.84 | L3MBTL1 (0.46) | L3MBTL1ELANEDTYMKBRD4POLB | |
| SCHEMBL1267232 | 0.84 | ELANE (0.46) | L3MBTL1ELANEDTYMKBRD4POLB | |
| SCHEMBL3762275 | 0.82 | ELANE (0.47) | L3MBTL1ELANEDTYMKBRD4POLB | |
| SCHEMBL2018732 | 0.81 | L3MBTL1 (0.78) | L3MBTL1ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL29651147 | 0.81 | L3MBTL1 (0.78) | L3MBTL1ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL3757166 | 0.80 | ELANE (0.43) | L3MBTL1ELANEDTYMKBRD4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032578-A2 | TRIAZOLOPYRIDAZINE DERIVATIVES | Pfizer Products Incorporated (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007138472-A2 | TRIAZOLOPYRIDAZINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007138472-A2 | TRIAZOLOPYRIDAZINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-12-06 | — | — | WO | disclosed |