SCHEMBL304587

SCHEMBL304587

Cc1cc(O)c(N)cc1Br

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.43
ALOX15 P16050 4/20 0.43
HSD17B10 Q99714 3/20 0.43
CYP3A4 P08684 5/20 0.40
TSHR P16473 3/20 0.40
MAPK1 P28482 2/20 0.40
MAPT P10636 5/20 0.38
GAA P10253 5/20 0.38
KDM4E B2RXH2 3/20 0.38
LMNA P02545 1/20 0.38
CASP1 P29466 1/20 0.38
PDE10A Q9Y233 1/20 0.38
PKM P14618 3/20 0.37
HIF1A Q16665 3/20 0.37
ALOX12 P18054 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
G6PD P11413 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1701096 0.91 TSHR (0.46) ALDH1A1ALOX15HSD17B10CYP3A4TSHR
SCHEMBL22401850 0.83 CYP3A4 (0.48) ALDH1A1ALOX15HSD17B10CYP3A4TSHR
SCHEMBL31634593 0.82 CYP3A4 (0.52) ALDH1A1ALOX15HSD17B10CYP3A4TSHR
SCHEMBL5884188 0.82 CYP3A4 (0.52) ALDH1A1ALOX15HSD17B10CYP3A4TSHR
Hydrochloric Acid SCHEMBL28575331 0.80 CYP3A4 (0.50) ALDH1A1ALOX15HSD17B10CYP3A4TSHR
SCHEMBL3046974 0.79 CYP3A4 (0.55) ALDH1A1ALOX15HSD17B10CYP3A4TSHR
SCHEMBL1199708 0.79 CYP3A4 (0.63) ALDH1A1ALOX15HSD17B10CYP3A4TSHR
SCHEMBL2955553 0.79 CYP3A4 (0.55) ALDH1A1ALOX15HSD17B10CYP3A4TSHR
SCHEMBL31387618 0.79 CYP3A4 (0.63) ALDH1A1ALOX15HSD17B10CYP3A4TSHR
SCHEMBL68996 0.79 ALOX15 (0.43) ALDH1A1ALOX15HSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111952549-B Carbon-coated lithium battery negative electrode material with yolk-eggshell structure and preparation method thereof 宝山钢铁股份有限公司 2021-08-17 CN claimed
CN-111952549-A Carbon-coated lithium battery negative electrode material with yolk-eggshell structure and preparation method thereof 宝山钢铁股份有限公司 2020-11-17 CN claimed
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed
CN-119948034-A Novel peptide-based nitrile compound and application thereof 上海壹迪生物技术有限公司 2025-05-06 CN disclosed
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 EP disclosed
CN-119730846-A Kinase modulators and methods of use thereof 神经元23公司 2025-03-28 CN disclosed
WO-2023244788-A9 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2024-09-12 WO disclosed
CN-117964637-A Novel peptide-based nitrile compound and application thereof 上海壹迪生物技术有限公司 2024-05-03 CN disclosed
WO-2024088307-A1 NOVEL PEPTIDYL NITRILE COMPOUND AND USE THEREOF 上海壹迪生物技术有限公司 2024-05-02 WO disclosed
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF SUNDANCE BIOSCIENCES, INC. 2024-01-25 US disclosed
WO-2023244788-A1 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2023-12-21 WO disclosed
WO-2014203217-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS AS CRAC MODULATORS LUPIN LIMITED (IN) 2014-12-24 WO disclosed
US-20140206663-A1 TRIAZINONE COMPOUNDS WUXI APPTECH (SHANGHAI) CO., LTD. (CN) 2014-07-24 US disclosed
US-8093238-B2 Fused thiazole derivatives as kinase inhibitors UCB PHARMA S.A. (BE) 2012-01-10 US disclosed
US-20100069361-A1 Fused Thiazole Derivatives as Kinase Inhibitors UCB PHARMA S.A. (BE) 2010-03-18 US disclosed
EP-2076512-A1 FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS UCB Pharma S.A. (BE) 2009-07-08 EP disclosed
WO-2008044022-A1 FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS UCB PHARMA S.A. (BE) 2008-04-17 WO disclosed
EP-0141377-B1 METAL COMPLEXES HODOGAYA CHEMICAL CO., LTD. (JP) 1990-05-02 EP disclosed
US-4563409-A ELECTROGRAPHY HOGOHAYA CHEMICAL CO., LTD. (JP) 1986-01-07 US disclosed
EP-0141377-A2 Metal complexes HODOGAYA CHEMICAL CO., LTD. (JP) 1985-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140206663-A1 TRIAZINONE COMPOUNDS THPO, IL5, CYP11B2 ALDH1A1 462/4885ALOX15 1205/4885HSD17B10 1140/4885
US-20100069361-A1 Fused Thiazole Derivatives as Kinase Inhibitors JAK1, MTOR, MOK ALDH1A1 1714/4885ALOX15 1219/4885HSD17B10 2961/4885
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP9, DPP7, DPP4 ALDH1A1 245/4885ALOX15 2760/4885HSD17B10 172/4885
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF TYK2, JAK1, JAK3 ALDH1A1 4807/4885ALOX15 3189/4885HSD17B10 3762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.