Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 5/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30789852 | 0.93 | ALDH1A1 (0.39) | HTR2AHTR2CHTR2BPARP1IKZF1 | |
| SCHEMBL30790177 | 0.89 | HTR2C (0.38) | HTR2AHTR2CHTR2BPARP1IKZF1 | |
| SCHEMBL30790468 | 0.83 | HTR2C (0.51) | HTR2AHTR2CHTR2BPARP1KMT2A | |
| SCHEMBL30790152 | 0.83 | PARP1 (0.40) | HTR2AHTR2CHTR2BPARP1IKZF1 | |
| SCHEMBL30459017 | 0.82 | HTR2C (0.46) | HTR2AHTR2CHTR2BPARP1IKZF1 | |
| SCHEMBL30790625 | 0.82 | CRBN (0.47) | HTR2AHTR2CHTR2BPARP1IKZF1 | |
| SCHEMBL32667474 | 0.79 | IKZF1 (0.60) | IKZF1 | |
| SCHEMBL26109177 | 0.78 | IKZF1 (0.49) | IKZF1 | |
| SCHEMBL30459129 | 0.78 | HTR2B (0.44) | HTR2AHTR2CHTR2BPARP1IKZF1 | |
| SCHEMBL30458379 | 0.78 | HTR2B (0.44) | HTR2AHTR2CHTR2BPARP1IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032689-A1 | COMPOUND BASED ON ISOINDOLINE-SUBSTITUTED GLUTARIMIDE BACKBONE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-02-15 | — | — | WO | claimed |