Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 4/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17683078 | 0.85 | CDK5 (0.49) | CDK5CDK5R1CCNT1CDK9BRD4 | |
| SCHEMBL30129257 | 0.85 | CDK5 (0.49) | CDK5CDK5R1CCNT1CDK9BRD4 | |
| SCHEMBL30598645 | 0.78 | BRD4 (0.41) | CDK5CDK5R1CCNT1CDK9BRD4 | |
| SCHEMBL28939744 | 0.73 | EGFR (0.52) | CDK5CDK5R1CCNT1CDK9DYRK1A | |
| SCHEMBL29419125 | 0.73 | MKNK1 (0.50) | CDK5CDK5R1CCNT1CDK9DYRK1A | |
| SCHEMBL5096322 | 0.73 | MKNK1 (0.50) | CDK5CDK5R1CCNT1CDK9DYRK1A | |
| SCHEMBL30337182 | 0.73 | CDK5 (0.51) | CDK5CDK5R1CCNT1CDK9DYRK1A | |
| SCHEMBL5750318 | 0.73 | CDC7 (0.60) | CDK5CDK5R1CCNT1CDK9DYRK1A | |
| SCHEMBL29870510 | 0.73 | CDC7 (0.60) | CDK5CDK5R1CCNT1CDK9DYRK1A | |
| SCHEMBL29800582 | 0.73 | EGFR (0.52) | CDK5CDK5R1CCNT1CDK9DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |