SCHEMBL30459200

SCHEMBL30459200

[2H]c1cc2c(cc1Br)C(=O)N(C1CCC(=O)NC1=O)C2

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.69
DDB1 Q16531 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21855270 0.89 CRBN (0.77) CRBNDDB1
SCHEMBL29439987 0.89 CRBN (0.77) CRBNDDB1
SCHEMBL22034379 0.89 CRBN (0.77) CRBNDDB1
SCHEMBL30458312 0.86 CRBN (0.65) CRBNDDB1
SCHEMBL4449425 0.81 CRBN (0.73) CRBNDDB1
SCHEMBL31726960 0.81 CRBN (0.73) CRBNDDB1
SCHEMBL29614623 0.81 CRBN (0.73) CRBNDDB1
SCHEMBL27305814 0.81 CRBN (0.73) CRBNDDB1
SCHEMBL29439976 0.81 CRBN (1.00) CRBN
SCHEMBL21760366 0.81 CRBN (1.00) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023104155-A1 LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF 标新生物医药科技(上海)有限公司 2023-06-15 WO claimed