Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 12/20 | 0.79 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.49 |
| ▸ | JAK1 | P23458 | 2/20 | 0.49 |
| ▸ | TYK2 | P29597 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938295 | 1.00 | KMO (0.79) | KMOGRM4MEN1KMT2ALMNA | |
| SCHEMBL1939177 | 0.88 | KMO (1.00) | KMOGRM4MEN1KMT2ASMO | |
| SCHEMBL1938796 | 0.87 | KMO (0.75) | KMOGRM4SMO | |
| SCHEMBL30429642 | 0.87 | KMO (0.75) | KMOGRM4SMO | |
| SCHEMBL1939398 | 0.86 | KMO (0.77) | KMOGRM4SMO | |
| SCHEMBL1937820 | 0.85 | KMO (0.76) | KMOGRM4MAPK1 | |
| SCHEMBL1938480 | 0.84 | KMO (0.64) | KMOGRM4MEN1KMT2APOLB | |
| SCHEMBL30429433 | 0.84 | KMO (0.64) | KMOGRM4MEN1KMT2APOLB | |
| SCHEMBL1939192 | 0.83 | KMO (0.59) | KMOGRM4LMNA | |
| SCHEMBL30459555 | 0.83 | KMO (0.59) | KMOGRM4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323583-A | Heterobiaryl compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2023-06-23 | — | — | CN | disclosed |