Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 1/20 | 0.52 |
| ▸ | CCND1 | P24385 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CCND3 | P30281 | 1/20 | 0.52 |
| ▸ | MAPK4 | P31152 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | CDK7 | P50613 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1940152 | 1.00 | KMO (0.63) | KMOMAPTPIK3CDPIK3C2BAURKA | |
| SCHEMBL30429389 | 0.85 | MGAM (0.61) | KMOMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1938305 | 0.85 | MGAM (0.61) | KMOMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1938405 | 0.82 | KMO (0.62) | KMOKDM4EALDH1A1 | |
| SCHEMBL30428941 | 0.82 | KMO (0.62) | KMOKDM4EALDH1A1 | |
| SCHEMBL14742157 | 0.79 | KMO (0.71) | KMO | |
| SCHEMBL1938295 | 0.79 | KMO (0.79) | KMOMAPK1LMNAMEN1KMT2A | |
| SCHEMBL30459265 | 0.79 | KMO (0.79) | KMOMAPK1LMNAMEN1KMT2A | |
| SCHEMBL14742111 | 0.78 | KMO (0.70) | KMOMAPTRAB9ALMNAKDM4E | |
| SCHEMBL30428813 | 0.78 | KMO (0.60) | KMOKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323583-A | Heterobiaryl compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2023-06-23 | — | — | CN | disclosed |