Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433220 | 0.83 | CHRNB2 (0.53) | CA1CHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL29450150 | 0.83 | CHRNB2 (0.53) | CA1CHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL166716 | 0.83 | CHRNB2 (0.53) | CA1CHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL3503155 | 0.83 | CHRNB2 (0.53) | CA1CHRNB2CHRNA7CHRNA4KMT2A | |
| Hydrochloric Acid SCHEMBL450686 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA7CHRNA4KMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL450685 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA7CHRNA4KMT2AHTR2A | |
| SCHEMBL433482 | 0.78 | MEN1 (0.54) | CHRNB2CHRNA7CHRNA4KMT2ASMN1; SMN2 | |
| SCHEMBL29891721 | 0.78 | CHRNB2 (0.41) | CA1CHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL21523837 | 0.77 | CHRNB2 (0.48) | CA1CHRNB2CHRNA4TAAR1HTR2A | |
| SCHEMBL432589 | 0.77 | CA1 (0.39) | CA1CHRNB2CHRNA7CHRNA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |