Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 8/20 | 0.62 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | ATR | Q13535 | 2/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.47 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14742507 | 1.00 | KMO (0.62) | KMOGRM5ATRKCNQ3KCNQ2 | |
| SCHEMBL30428606 | 0.90 | KMO (0.58) | KMOATR | |
| SCHEMBL1938798 | 0.90 | KMO (0.58) | KMOATR | |
| SCHEMBL1939325 | 0.86 | KMO (0.64) | KMOGRM5ATRKCNQ3KCNQ2 | |
| SCHEMBL30429437 | 0.86 | KMO (0.64) | KMOGRM5ATRKCNQ3KCNQ2 | |
| SCHEMBL1939248 | 0.85 | KMO (0.65) | KMOKCNQ3KCNQ2KCNQ5KCNE1 | |
| SCHEMBL30428890 | 0.85 | KMO (0.65) | KMOKCNQ3KCNQ2KCNQ5KCNE1 | |
| SCHEMBL1938448 | 0.84 | KMO (0.61) | KMOGRM5KCNQ3KCNQ2KCNQ5 | |
| SCHEMBL30429304 | 0.84 | KMO (0.61) | KMOGRM5KCNQ3KCNQ2KCNQ5 | |
| SCHEMBL30429046 | 0.82 | KMO (0.65) | KMOGRM5KCNQ3KCNQ2MAPK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323583-A | Heterobiaryl compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2023-06-23 | — | — | CN | disclosed |