Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15648949 | 0.81 | AURKA (0.54) | SRD5A1AURKAKDRTYK2CA9 | |
| SCHEMBL25656352 | 0.74 | PARP10 (0.52) | SRD5A1PARP1JAK2 | |
| SCHEMBL24643279 | 0.72 | IKBKB (0.44) | SRD5A1AURKAIKBKBKDRHTR2C | |
| SCHEMBL30812435 | 0.72 | IKBKB (0.44) | SRD5A1AURKAIKBKBKDRHTR2C | |
| SCHEMBL30459657 | 0.70 | CDK5 (0.41) | SRD5A1IKBKBKDRCA9CA12 | |
| SCHEMBL22904178 | 0.70 | TDP2 (0.64) | SRD5A1TDP2 | |
| SCHEMBL29376253 | 0.68 | CA12 (0.63) | SRD5A1CA9CA12PARP1TDP2 | |
| SCHEMBL15154660 | 0.68 | CA12 (0.63) | SRD5A1CA9CA12PARP1TDP2 | |
| SCHEMBL192783 | 0.68 | SRD5A1 (0.53) | SRD5A1TTRAADATCA9TYMS | |
| SCHEMBL30459565 | 0.68 | HTR2A (0.32) | HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |