Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.50 |
| ▸ | HTR2B | P41595 | 10/20 | 0.43 |
| ▸ | HTR2C | P28335 | 9/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496975 | 0.89 | PARP1 (0.50) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30004312 | 0.83 | PARP1 (0.41) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL27093617 | 0.83 | PARP1 (0.41) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30351817 | 0.80 | PARP1 (0.47) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30460068 | 0.79 | HTR2B (0.49) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30351699 | 0.79 | PARP1 (0.47) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30695894 | 0.77 | HTR2C (0.49) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL25228753 | 0.77 | HTR2A (0.33) | PARP1HTR2BHTR2CHTR2APOLB | |
| SCHEMBL30352021 | 0.76 | PARP1 (0.44) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30352272 | 0.76 | PARP1 (0.44) | PARP1HTR2BHTR2CHTR2AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |