Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25214505 | 0.92 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDHSD17B10APLNR | |
| SCHEMBL25213343 | 0.90 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDHSD17B10APLNR | |
| SCHEMBL25436972 | 0.88 | APLNR (0.31) | ALDH1A1MAPTHPGDHSD17B10APLNR | |
| SCHEMBL25801788 | 0.86 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDHSD17B10THRB | |
| SCHEMBL25213831 | 0.86 | APLNR (0.33) | ALDH1A1MAPTHPGDHSD17B10APLNR | |
| SCHEMBL23588038 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDHSD17B10THRB | |
| SCHEMBL25433250 | 0.85 | TP53 (0.32) | ALDH1A1MAPTHPGDHSD17B10APLNR | |
| SCHEMBL25801811 | 0.83 | ALDH1A1 (0.37) | ALDH1A1THRBTHRA | |
| SCHEMBL25270070 | 0.83 | APLNR (0.34) | ALDH1A1MAPTHPGDHSD17B10APLNR | |
| SCHEMBL25299009 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDHSD17B10THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192821-A1 | ALPHA,BETA UNSATURATED METHACRYLIC ESTERS WITH ANTI-INFLAMMATORY PROPERTIES | Sitryx Therapeutics Limited (GB) | 2023-06-14 | — | — | EP | disclosed |