Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25348661 | 1.00 | PDE4D (0.41) | PDE4DKDM1AADORA2AHDAC6KDM1B | |
| SCHEMBL25351650 | 0.89 | HDAC6 (0.47) | PDE4DKDM1AADORA2AHDAC6HDAC1 | |
| SCHEMBL30460211 | 0.89 | HDAC6 (0.47) | PDE4DKDM1AADORA2AHDAC6HDAC1 | |
| SCHEMBL30460216 | 0.89 | HDAC1 (0.43) | PDE4DKDM1AADORA2AHDAC6KDM1B | |
| SCHEMBL25348693 | 0.89 | HDAC1 (0.43) | PDE4DKDM1AADORA2AHDAC6KDM1B | |
| SCHEMBL30409806 | 0.89 | MET (0.39) | PDE4DHDAC6HDAC1 | |
| SCHEMBL30460311 | 0.89 | MET (0.39) | PDE4DHDAC6HDAC1 | |
| SCHEMBL25993814 | 0.89 | MET (0.39) | PDE4DHDAC6HDAC1 | |
| SCHEMBL25349667 | 0.88 | GPR119 (0.41) | KDM1AHDAC6MAPT | |
| SCHEMBL30460457 | 0.88 | GPR119 (0.41) | KDM1AHDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |