Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | USP1 | O94782 | 18/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27088282 | 1.00 | AGTR1 (0.41) | AGTR1AGTR2USP1PDE2A | |
| SCHEMBL25430434 | 0.88 | PDE2A (0.41) | USP1PDE2A | |
| SCHEMBL25976056 | 0.88 | USP1 (0.43) | USP1PDE2A | |
| SCHEMBL26627859 | 0.88 | PDE2A (0.43) | USP1PDE2A | |
| SCHEMBL30461997 | 0.88 | PDE2A (0.43) | USP1PDE2A | |
| SCHEMBL31368667 | 0.87 | USP1 (0.41) | USP1 | |
| SCHEMBL29043914 | 0.87 | USP1 (0.41) | USP1 | |
| SCHEMBL30462059 | 0.87 | PDE2A (0.42) | USP1PDE2A | |
| SCHEMBL29043903 | 0.87 | PDE2A (0.42) | USP1PDE2A | |
| SCHEMBL27088279 | 0.86 | USP1 (0.40) | USP1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118660872-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-116496252-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2023-07-28 | — | — | CN | disclosed |