Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21684236 | 0.85 | PTK2 (0.41) | PTK2ALDH1A1 | |
| SCHEMBL16037465 | 0.83 | PTK2 (0.35) | PTK2ALDH1A1 | |
| SCHEMBL9935799 | 0.83 | PTK2 (0.35) | PTK2ALDH1A1 | |
| SCHEMBL5507622 | 0.81 | PTK2 (0.50) | PTK2ALDH1A1 | |
| SCHEMBL16127181 | 0.79 | CYP3A4 (0.40) | PTK2ALDH1A1 | |
| SCHEMBL27246730 | 0.79 | POLB (0.32) | PTK2 | |
| SCHEMBL23830130 | 0.74 | CA1 (0.30) | PTK2 | |
| SCHEMBL15300754 | 0.72 | KDM1A (0.32) | ALDH1A1 | |
| SCHEMBL22832006 | 0.72 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL24121182 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924343-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS | Merck Sharp & Dohme Corp. (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2010036613-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS | MERCK SHARP & DOHME CORP. (US) | 2010-04-01 | — | — | WO | disclosed |